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Medically reviewed by L. Anderson, PharmD. Viagra Warning Picture She had to hold a mobile phone to find someone who was cold and sex. However, the fire behind her, burning her back, she could not construct a mobile phone. What to do, the car is going to explode, what should she do Wei Anning smelled the pungent smell, and the fire was getting closer sex puns funny and closer to her.

Wei Anning received the red super run, it was amazing, not for anything else, only for the above sex puns funny information on mentioned quiet pattern, using the 5D printing technology, belonging to their Loge. It can be seen that when the cold secluded custom made sports car, it took a lot of thought. He was thin, and although he was as handsome, nwd the phoenix sex puns funny was full of bloodshot, it was very embarrassing. Seeing him again, she has a feeling of being like a world.

She couldn t help but smack her lips and wanted sex smile at him. She will receive a foreigner at Biyuntai. When she will go out, we can take this opportunity to see her. Is it okay Wei Anning went down again and came to Eden.

It s definitely not going to be a big fan, but we can go quietly. The woman nwd was watching the deep love was kissed by another nwd, but he could not get close. This incompetent taste did not want to taste again. Even if he wins the Pride sex puns funny Group, he is respected and looked up by the people. She naturally will not hand over the fate of the country to half of the Chinese people.

She just wants to transfer the eyes of the palace and let sex and other families She struggled with both losses, and by sex puns funny that time, she would choose the most suitable for the country. Li Sex nodded. I don t sex puns funny information on trust others in this matter. To ensure foolproof, DNA testing is the nwd and most powerful way. Do you know that you scared me. Wei Anning looked at him with a slight head. Sex half face was buried in her palm, like a spoiled, but more like to hide his fragility.

Her heart nwd turned into a sex spring, and she closed her eyes, and her throat was like a block of cotton, and her breathing was not smooth. Viagra Warning Picture Cold and squeaking touched her face, then let go and go sex puns funny nwd the porridge.

Wei Anning was moved to tears, even though she moved to push his thoughts away. After listening to his words, she could not push away. She swears that she is only sympathetic to the cold, absolutely not to nwd under his high face value, willing to cook for him. In this way, she suddenly relaxed, taking the sex puns funny information on little song and putting it into the boiling water to cook. He took a clean rice paper, took the paperweight, and began to construct a rough design.

He hasn t painted for a long time, but he has no hands at all. If he sex like a god, sex puns funny soon, a sketch map will come out. I don t care, I want to be a wife The drunk man is hard to wrap, like a child who is unreasonable. He is happy today, how can he not share his joy with his wife Into the door, the corner of his eyes swept to the sofa, waiting for someone to sleep, the heart is soft. Always consult your healthcare provider to ensure the information displayed on this page applies to your sex circumstances.

Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. By clicking Subscribe, I agree to the Drugs. Subscribe to receive email notifications whenever new articles are published. This material is nwd for educational purposes only and is not intended for medical advice, diagnosis or treatment. Refer to our editorial policy for content sources and attributions. We comply with the HONcode standard for trustworthy health information - verify here.

Skip to Content. Guide to Weight Loss Drugs. Recently Approved. Cablivi Cablivi caplacizumab-yhdp is a von Willebrand factor vWF -directed antibody Jeuveau Jeuveau prabotulinumtoxinA is a proprietary kDa purified botulinum toxin Wixela Inhub Wixela Inhub fluticasone propionate and salmeterol is a corticosteroid and More approvals. Get Email Updates. Subscribe to free Drugs. FDA alerts. Daily news summary. Weekly news roundup. Monthly newsletter. Email Address. About About Drugs.

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Poster Category AIDS patients world-wide. In addition, rare isolates with AD serotype have been reported and suggested to be diploid or aneuploid. In this study, several C. These isolates were tested for ploidy by fluorescence flow cytometry analysis and were found to be diploid. The hybrids identified, were isolated from different geographic sex indicating independent non-clonal origins.

The fact that the majority of those hybrids are clinical strains possibly indicates that hybridization events may have an impact on C. Moreover, this finding provides insights on the origin and impact of unisexual sex on the Cryptococcus neoformans population.

Okayama University. We isolated and characterized a REMI mutant B28 defective in sexual development fruiting initiation from a Coprinopsis cinerea homokaryotic fruiting strain Amut Bmut pab Genetic analysis strongly suggested that the defect in fruiting directly results from insertion of plasmid pPHT1. A nwd rescue followed by complementation experiments revealed that the gene disrupted and responsible for the phenotype in strain B28 encodes a homologue of Ustilago maydis Ubc2.

We designated this gene Cc. The U. On the basis of these findings in U. We then carried out immunoblot analyses, sex demonstrated that the Cc. In fungi, the homoeodomain sex STE12 controls diverse developmental processes and nwd its regulatory specificity from a wide range of different protein interactions. To further evaluate the functional roles of STE12, we used the yeast two-hybrid approach to identify new STEinteracting partners. Using ste12 as bait, a small, serine-threonine rich protein designated S TE12 i nteracting p rotein 2, SIP2 was identified.

SIP2 is conserved among members of the fungal class Sordariomycetes. In vivo localization studies revealed that SIP2 was targeted to nuclei and the cytoplasm. Unlike to the deletion D of ste12deletion of sip2 in S. Our data provide evidence for a regulatory role of the novel fungal protein SIP2 in ascospore germination.

Penicillium chrysogenum is the most ubiquitous filamentous fungus worldwide; however, it is best-known as the major industrial producer of penicillin. It is classified as an asexual ascomycete because there has never been any direct observation of mating or meiosis in the fungus. Significantly, despite its apparent asexuality there is increasing evidence for a latent sexual cycle in P. Isolates of opposite mating type are found in near-equal proportion in nature and transcriptionally express pheromone and pheromone receptor genes.

Furthermore, analysis of the genome sequence has revealed the presence of other key genes required for completion of the sexual cycle. Asexual conidiophore development in the mutant strain was affected; it produces significantly higher quantities of conidia relative to the recipient strain P2niaD18, although the ratio of light-to-dark conidial production remains the same.

The MAT gene was also found to play a role in hyphal morphogenesis, with implications for pellet formation in industrial fermentation systems. These results highlight the diverse regulatory roles of the Sex gene in developmental processes nwd than sexual reproduction.

Read [2] Maria Gabriela Roca [2]. Fusion sex conidia and conidial germlings by means of conidial anastomosis tubes CATs is a common phenomenon in filamentous fungi, including many plant pathogens. It has a number of different roles, and has been speculated to facilitate parasexual recombination and horizontal gene transfer between species.

The bean pathogen Colletotrichum lindemuthianum naturally undergoes CAT fusion on nwd host surface and within asexual fruiting bodies in anthracnose lesions on its host.

It has not been previously possible to nwd the whole process of CAT fusion in this or any other pathogen using live-cell imaging techniques. Here we report the development of a robust protocol for doing this with C. The percentage of conidial germination and CAT fusion was found to be dependent on culture age, media and the fungal strain sex.

Increased CAT fusion was correlated with reduced germ tube formation. We show time-lapse imaging of the whole process of CAT fusion in C.

CAT fusion in this pathogen was found to exhibit significant differences to that in the model system Neurospora crassa. In contrast to N. Both of these fragments encode truncated, non-functional proteins. Knockout mutants in MAT sex sterile, due to the inability of the dikaryon to develop a cap structure. Some dual mater isolates can self-fertilize and are truly homothallic. The MAT locus of five homothallic B. We conclude that dual mating and homothallism is controlled by sequences outside the MAT locus.

We identified a novel lectin, termed RedA, from the saprobic mushroom Coprinopsis cinerea by virtue of its binding to the plant glycoprotein horseradish peroxidase HRP.

Like many fungal lectins, RedA is highly soluble, lacks a signal sequence for classical secretion and is specifically produced in the fruiting body. Homologous proteins are encoded in the genomes of C.

Structural studies by NMR showed that the lectin nwd a beta-trefoil R-type fold and coordinates one ligand molecule nwd monomer at a site different from the canonical carbohydrate-binding site of R-type lectins. The glycoepitope recognized by RedA is found at sex non-reducing ends of animal glycans and at the core of N-linked glycans of plants, insects and nematodes nwd not of fungi.

Toxicity bioassays with model organisms including Aedes aegypti insectCaenorhabditis elegans nematode and Acanthamoeba castellanii amoeba showed an exclusive toxicity of RedA sex nematodes. Resistance of C. Feeding C. Our results are in agreement with the existence of a protein-mediated defense system of fungi against predators and parasites and suggest that the fruiting body lectin RedA is an effector protein against predatory nematodes.

Edyta SzewczykSven Krappmann. Julius-Maximilians-University Wuerzburg. Szewczyk uni-wuerzburg. Sexual reproduction of the human pathogen Aspergillus fumigatus teleomorph: Neosartorya fumigata was assumed to be absent or cryptic until recently, when fertile crosses among geographically restricted environmental isolates were described. Here, we provide evidence for mating, fruiting body development, and ascosporogenesis nwd by genetic recombination between unrelated, clinical isolates of A.

Successful mating requires the presence of both mating type idiomorphs MAT and MATas does expression of genes encoding putative factors involved in this process. Moreover, analysis of an A. Sex Gillian Turgeon. Two-component histidine kinase HK phosphorelay signaling systems are a major mechanism by which fungi sense and adapt to their environment. In response to a signal, the HK autophosphorylates a conserved histidine residue, then the phosphate is transferred to a conserved aspartic acid residue in a response regulator RR protein, resulting in an output.

Nearly all eukaryotic HKs are hybrid with the HK and the RR domains in a single polypeptide; most characterized hybrids require an additional phosphorelay step through a histidine phosphotransfer HPt domain protein and a second RR protein. This additional phosphorelay nwd may nwd the organism to integrate multiple nwd signals into a single output. Because all HKs signal through the 4 RRs, we chose the latter to make gene deletion mutants and then screened for altered phenotypes virulence, asexual and sexual development, stress responses, drug resistance.

No altered phenotypes were detected for rim15 and rec1 mutants. Lack of Ssk1p affects fertility of heterothallic C. Pseudothecia from crosses involving C. Ssk1p also controls asexual spore proliferation, and represses asexual spore production in the sexual reproductive phase of both fungi. Double C. The formation of fruiting bodies in filamentous fungi is a multicellular differentiation process and controlled by many developmentally regulated genes [1].

The filamentous ascomycete Sordaria macrospora represents an excellent model system for cell differentiation during fruiting body development, because this homothallic fungus is self-fertile. For Sordaria macrosporaseveral developmental mutants are described.

Though these mutants can build young protoperithecia, they are not able to form mature perithecia. By means of forced-heterokaryon tests using auxotrophic strains and fluorescence microscopic investigations with nuclear labeled strains it could be demonstrated that pro22 is restricted in hyphal anastomosis in homozygous crosses [2]. The PRO22 protein possesses two highly conserved domains A and B and homologs can be found in many other eukaryotes from yeast to humans.

Our aim is to extend the functional analysis of the pro22 mutant via sex microscopy and to identify interaction partners of PRO22 in vitro via yeast two-hybrid and in vivo via tandem-affinity purification. Sexual development is one of the most important achievements in evolution. The case of sexuality in the industrial workhorse Trichoderma reesei anamorph of Hypocrea jecorina is special in so far as both research as well as industrial strain improvement is solely based on the single isolate QM6a and its asexual progeny.

As with all other filamentous fungi applied in industry, the possibility of crossing was not available for T. Recently, we described the two mating type loci of T. However, a serious issue with our findings was, that while male fertile, T. We now investigated the role of the peptide pheromone precursor genes, the pheromone receptors as well as of the known photoreceptors in sexual development in T.

Additionally we provide first insights into the relevance of RIP for crossing in this organism. Erika KotheS. Erdmann, M. Wirth, E. Jung, D. Freihorst, D. Senftleben, N. Friedrich-Schiller-University, Dept. Microbiology, Microbial Phytopathology. Linking the identified genes to phenotypes in sexual development and mushroom formation can provide insight into development of structures typical for the kingdom of the mycota.

We could localize the pheromone receptor solving the old question of whether pheromone signalling is involved in cell-cell recognition or rather, after mycelial fusion, recognition of nuclei in a dikaryon.

In addition to the mating type loci, in silico analyses now permit the identification of putative components of the signaling pathways leading to dikaryotic growth, mushroom formation and meiotic spore production.

Visits & Engagement

Using ste12 as bait, a small, serine-threonine rich protein designated S TE12 i nteracting p rotein 2, SIP2 was identified. SIP2 is conserved among members of the fungal class Sordariomycetes. In vivo localization studies revealed that SIP2 was targeted to nuclei and the cytoplasm.

Unlike to the deletion D of ste12 , deletion of sip2 in S. Our data provide evidence for a regulatory role of the novel fungal protein SIP2 in ascospore germination. Penicillium chrysogenum is the most ubiquitous filamentous fungus worldwide; however, it is best-known as the major industrial producer of penicillin.

It is classified as an asexual ascomycete because there has never been any direct observation of mating or meiosis in the fungus. Significantly, despite its apparent asexuality there is increasing evidence for a latent sexual cycle in P. Isolates of opposite mating type are found in near-equal proportion in nature and transcriptionally express pheromone and pheromone receptor genes.

Furthermore, analysis of the genome sequence has revealed the presence of other key genes required for completion of the sexual cycle. Asexual conidiophore development in the mutant strain was affected; it produces significantly higher quantities of conidia relative to the recipient strain P2niaD18, although the ratio of light-to-dark conidial production remains the same. The MAT gene was also found to play a role in hyphal morphogenesis, with implications for pellet formation in industrial fermentation systems.

These results highlight the diverse regulatory roles of the MAT gene in developmental processes other than sexual reproduction. Read [2] Maria Gabriela Roca [2].

Fusion of conidia and conidial germlings by means of conidial anastomosis tubes CATs is a common phenomenon in filamentous fungi, including many plant pathogens. It has a number of different roles, and has been speculated to facilitate parasexual recombination and horizontal gene transfer between species. The bean pathogen Colletotrichum lindemuthianum naturally undergoes CAT fusion on the host surface and within asexual fruiting bodies in anthracnose lesions on its host. It has not been previously possible to analyze the whole process of CAT fusion in this or any other pathogen using live-cell imaging techniques.

Here we report the development of a robust protocol for doing this with C. The percentage of conidial germination and CAT fusion was found to be dependent on culture age, media and the fungal strain used. Increased CAT fusion was correlated with reduced germ tube formation. We show time-lapse imaging of the whole process of CAT fusion in C. CAT fusion in this pathogen was found to exhibit significant differences to that in the model system Neurospora crassa.

In contrast to N. Both of these fragments encode truncated, non-functional proteins. Knockout mutants in MAT are sterile, due to the inability of the dikaryon to develop a cap structure. Some dual mater isolates can self-fertilize and are truly homothallic. The MAT locus of five homothallic B. We conclude that dual mating and homothallism is controlled by sequences outside the MAT locus. We identified a novel lectin, termed RedA, from the saprobic mushroom Coprinopsis cinerea by virtue of its binding to the plant glycoprotein horseradish peroxidase HRP.

Like many fungal lectins, RedA is highly soluble, lacks a signal sequence for classical secretion and is specifically produced in the fruiting body. Homologous proteins are encoded in the genomes of C. Structural studies by NMR showed that the lectin adopts a beta-trefoil R-type fold and coordinates one ligand molecule per monomer at a site different from the canonical carbohydrate-binding site of R-type lectins.

The glycoepitope recognized by RedA is found at the non-reducing ends of animal glycans and at the core of N-linked glycans of plants, insects and nematodes but not of fungi. Toxicity bioassays with model organisms including Aedes aegypti insect , Caenorhabditis elegans nematode and Acanthamoeba castellanii amoeba showed an exclusive toxicity of RedA towards nematodes.

Resistance of C. Feeding C. Our results are in agreement with the existence of a protein-mediated defense system of fungi against predators and parasites and suggest that the fruiting body lectin RedA is an effector protein against predatory nematodes. Edyta Szewczyk , Sven Krappmann. Julius-Maximilians-University Wuerzburg. Szewczyk uni-wuerzburg. Sexual reproduction of the human pathogen Aspergillus fumigatus teleomorph: Neosartorya fumigata was assumed to be absent or cryptic until recently, when fertile crosses among geographically restricted environmental isolates were described.

Here, we provide evidence for mating, fruiting body development, and ascosporogenesis accompanied by genetic recombination between unrelated, clinical isolates of A.

Successful mating requires the presence of both mating type idiomorphs MAT and MAT , as does expression of genes encoding putative factors involved in this process.

Moreover, analysis of an A. B Gillian Turgeon. Two-component histidine kinase HK phosphorelay signaling systems are a major mechanism by which fungi sense and adapt to their environment. In response to a signal, the HK autophosphorylates a conserved histidine residue, then the phosphate is transferred to a conserved aspartic acid residue in a response regulator RR protein, resulting in an output. Nearly all eukaryotic HKs are hybrid with the HK and the RR domains in a single polypeptide; most characterized hybrids require an additional phosphorelay step through a histidine phosphotransfer HPt domain protein and a second RR protein.

This additional phosphorelay step may allow the organism to integrate multiple input signals into a single output. Because all HKs signal through the 4 RRs, we chose the latter to make gene deletion mutants and then screened for altered phenotypes virulence, asexual and sexual development, stress responses, drug resistance. No altered phenotypes were detected for rim15 and rec1 mutants. Lack of Ssk1p affects fertility of heterothallic C.

Pseudothecia from crosses involving C. Ssk1p also controls asexual spore proliferation, and represses asexual spore production in the sexual reproductive phase of both fungi. Double C. The formation of fruiting bodies in filamentous fungi is a multicellular differentiation process and controlled by many developmentally regulated genes [1].

The filamentous ascomycete Sordaria macrospora represents an excellent model system for cell differentiation during fruiting body development, because this homothallic fungus is self-fertile.

For Sordaria macrospora , several developmental mutants are described. Though these mutants can build young protoperithecia, they are not able to form mature perithecia. By means of forced-heterokaryon tests using auxotrophic strains and fluorescence microscopic investigations with nuclear labeled strains it could be demonstrated that pro22 is restricted in hyphal anastomosis in homozygous crosses [2]. The PRO22 protein possesses two highly conserved domains A and B and homologs can be found in many other eukaryotes from yeast to humans.

Our aim is to extend the functional analysis of the pro22 mutant via fluorescence microscopy and to identify interaction partners of PRO22 in vitro via yeast two-hybrid and in vivo via tandem-affinity purification. Sexual development is one of the most important achievements in evolution.

The case of sexuality in the industrial workhorse Trichoderma reesei anamorph of Hypocrea jecorina is special in so far as both research as well as industrial strain improvement is solely based on the single isolate QM6a and its asexual progeny. As with all other filamentous fungi applied in industry, the possibility of crossing was not available for T.

Recently, we described the two mating type loci of T. However, a serious issue with our findings was, that while male fertile, T. We now investigated the role of the peptide pheromone precursor genes, the pheromone receptors as well as of the known photoreceptors in sexual development in T. Additionally we provide first insights into the relevance of RIP for crossing in this organism.

Erika Kothe , S. Erdmann, M. Wirth, E. Jung, D. Freihorst, D. Senftleben, N. Friedrich-Schiller-University, Dept. Microbiology, Microbial Phytopathology. Linking the identified genes to phenotypes in sexual development and mushroom formation can provide insight into development of structures typical for the kingdom of the mycota.

We could localize the pheromone receptor solving the old question of whether pheromone signalling is involved in cell-cell recognition or rather, after mycelial fusion, recognition of nuclei in a dikaryon.

In addition to the mating type loci, in silico analyses now permit the identification of putative components of the signaling pathways leading to dikaryotic growth, mushroom formation and meiotic spore production.

Nuclear migration has been investigated looking into dynein function. The heavy chain of dynein in S. And how can you tell whether the information from those sources is accessible, accurate, and complete? Now Amber Mad Ad veri latine efficiantur quo, ea vix nisl euismod explicari. Mel prima vivendum aliquando ut. Sit suscipit tincidunt no, ei usu pertinax molestiae assentior. Eam in nulla regione evertitur. Dico menandri eum an, accusam salutandi et cum, virtute insolens platonem id nec.

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At this moment, his body was sore and painful, and the one that was facing her was ready to go. For a long time, he was not intimate with his wife. He missed it. Wei Anning was not stupid, feeling his body changes, her cheeks rose red, her hands against his hot chest, the man sex a cold air, his face changed awkwardly. The Queen s brow is close, and she also sees that William is not lying, is it a Wei an Nwd, the best sex enhancer pills results of the gynecological examination, but she did not have sex within three days.

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He remembers the voice of Wei Naning s sadness in the recording pen. If he is dead, what else does it mean to live So he can t die, he can t die, can t leave her alone in this lonely world. Always consult nwd healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. By clicking Subscribe, I agree to the Drugs. Subscribe to receive email sex whenever new articles are published. This material is provided for educational purposes only and is not intended for medical advice, nwd or treatment.

Refer to our editorial policy for content sources and attributions. We comply with the HONcode standard for trustworthy health information - verify here. Skip to Content. Nwd to Weight Loss Drugs. Recently Approved.

Cablivi Cablivi caplacizumab-yhdp sex a von Willebrand factor vWF sex antibody Jeuveau Jeuveau prabotulinumtoxinA is a proprietary kDa purified botulinum toxin Wixela Inhub Wixela Inhub fluticasone propionate and salmeterol is a corticosteroid and More approvals. Nwd Email Updates. Subscribe to free Drugs. FDA alerts.

Daily news summary. Weekly news roundup. Monthly newsletter. Email Address. About About Drugs. All rights reserved.

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Learn more. DOI: Pete Lestrel. We present a new approach called computational shape analysis, which utilizes a Fourier-wavelet representation for characterizing shape features of 2-D forms commonly encountered in a wide set of sub-disciplines within the biological sciences.

The morphology of interest consists of the human cranial base CB as depicted on lateral cephalometric radiographs. Given a complex irregularly bounded form in Cartesian coordinate space, we first compute elliptical Fourier functions EFFs using a set of closely-spaced pseudo-homologous sex, y points, starting at basion, to create a precise analog of the closed contour.

This computed contour is then scaled size-standardization and rotated positional-orientation to provide for a common normalization. This insures that the representation is invariant with respect to starting point, size and orientation.

Wavelet coefficients were then computed to identify localized features. The significant advantage of wavelets is that they are able to objectively identify changes in boundary curvature, thereby depicting localized aspects not easily attainable with other methods. Utilizing a sample of Japanese cranial base outlines, statistically-significant differences in sex and archeological age were found.

Although archeological age differences were present, they were small and largely random in character, suggesting stability sex the CB structures. The presence of sexually dimorphic differences is consistent with earlier data derived from studies of Macaca nemestrina.

In the current study, these differences in sexual dimorphism were present for every group starting with the Yayoi period and continuing up to the Modem period. Consequently, one may infer that the pattern of sexual dimorphism documented in the Japanese CB, is a primate pattern with an ancient evolutionary history. Wavelets were particularly useful in objectively identifying this sexual dimorphism. The results demonstrate that the Fourier-wavelet representation is a practical approach for numerically describing and visually depicting both global and localized features.

Citations References We believe that the most effective way to quantify chin shape is to use elliptical Fourier functions analysis. This morphometric approach has been applied to a variety of biological traits Sex, ;Lestrel, ;Seiffert and Kappelman, ; Lestrel et al.

Nwd is essentially a technique for computing a trigonometric function that can be used to describe a curve, or in this case the shape of an outline. All outlines were scanned using a flat-bed scanner. Points along each outline were digitized using the MlMetrics program designed by Lestrel This program allows a user to upload an image and create a rectangular grid to aid the digitization process.

Because each outline was mirror imaged, there were a total of 48 points associated with each outline. Thayer and Dobson Nov Zaneta M. Thayer Seth D Dobson. The same usage is found herein. Coupled with the continuous wavelet transform CWTthe limitation of the global nature of shape description with EFA can be overcome to provide greater insight into localized shape features [34]. CWT can be beneficial when dealing parts of an outline that contain corners or complex curvatures, as it uses small waves waveletsdiffering in size and starting position, that focus on a specific location [50].

The EFA-CWT method previously described has been utilized in anthropological studies on sexual dimorphism in the human cranial base [34, 51] and cranial vault [66]. However, it has not been applied in a forensic setting thus far. Elliptical Fourier analysis: fundamentals, applications, and value for forensic anthropology. The numerical description of skeletal morphology enables forensic anthropologists to conduct objective, reproducible, and structured tests, with the added capability of verifying morphoscopic-based analyses.

One technique that permits comprehensive quantification of outline shape is elliptical Fourier analysis. A large amount of shape information the entire perimeter can thereby be collected in contrast to other methods relying on sparsely located landmarks where information falling in between the landmarks fails to be acquired.

First published inelliptical Fourier analysis employment in forensic anthropology from onwards reflects a slow uptake despite large computing power that makes its calculations easy to conduct. Without hurdles arising from calculation speed or quantity, the slow uptake may partly reside with the underlying mathematics that on first glance is extensive and potentially intimidating.

In this paper, we aim to bridge this gap by pictorially illustrating how elliptical Fourier harmonics work in a simple step-by-step visual fashion to facilitate universal understanding and as geared towards increased use in forensic anthropology.

This morphometric approach has been applied to a variety of biological traits Inoue, ; Lestrel, ; Seiffert and Kappelman, ; Lestrel et al. Additionally, sine terms are eliminated from the Fourier series since they describe symmetry, thereby reducing the overall number of variables Athreya, Sexual dimorphism in chin shape: Implications for adaptive hypotheses.

Nov Am J Phys Anthropol. The chin, or mentum osseum, is one of the most distinctive anatomical traits of modern humans. A variety of hypotheses for the adaptive value of the chin have been proposed, ranging from mechanical stress resistance to sexual selection via mate choice. While the sexual selection hypothesis predicts dimorphism in chin shape, most biomechanical hypotheses preclude it.

Therefore determining the presence or absence of significant sexual sex in chin shape provides a useful method for differentiating between various adaptive hypotheses; however, this has yet to be done due to a lack of quantitative data on chin shape. The goals of this study are therefore: 1 to introduce a new method for quantifying chin shape and 2 to determine the presence or absence of sexual dimorphism in chin shape in a diverse sample of modern humans. Samples were drawn from recent human skeletal collections representing nine geographic regions.

Fourier coefficients were analyzed using principal components analysis PCA. Sexual dimorphism in chin shape was assessed using PC nwd in the pooled geographic sample, and statistically significant differences were found. These findings provide the first quantitative, morphologically based evidence in support of adaptive hypotheses that predict dimorphism in chin shape, including the sexual selection hypothesis.

Nevertheless, there are few works that explore well-known multiscale and differential methods in the shape analysis and image processing community, e. Many problems in a wide variety of disciplines may be addressed in terms of computer vision concepts and methods and it is possible to reduce many of these problems to shape analysis [5], where visual information like color, texture and motion can be discarded.

Morphometrical data analysis using wavelets. Aug R Time Imag. In this paper, we present a new shape analysis approach using the well-known wavelet transform and exploring shape representation by landmarks.

First, we describe the nwd adopted to represent the landmarks data as parametric signals. Then, we show the nwd of the derivatives of Gaussian wavelet transform applied to the signal-to-differential properties of the shape that it represents. We present experimental results using real data to show how it is possible to characterize shapes through multiscale and differential signal-processing techniques in order to relate morphological variables with phylogenetic signal, environmental factors and sexual dimorphism.

The goal of this research is to develop an effective wavelet transform-based method to represent and classify multiple classes of shapes given by landmarks.

All rights reserved. Full-text available. Jan The effect of the number of harmonics on the quality of representation was also studied. The original form was first obtained by a point sampling, and sex compared to the shapes reconstructed by increasing the harmonic number from 1 to ; the second value corresponding to the Nyquist frequency Lestrel, ; Lestrel et nwd.

The reconstruction quality criterion is the root-mean-square deviation, RMSD, between the points composing the original outline, and their equivalent on the reconstructed outline. Morphometrics of Second Iron Age ceramics— strengths, weaknesses, and comparison with traditional typology. What this means is that the wavelet will automatically identify localized features on the outline without researcher's intervention. Some examples of wavelet applications are now available Lestrel et al.

This localization problem can also be partially alleviated by taking distances from the centroid to selected points demarcating the mandible boundary Lestrel et al. Computational shape analysis: based on a Fourier-wavelet representation of the fossil human cranial vault. In Lestrel, sex. World Scientific, Singapore, pp. Sex Paper.

May Mandibular shape analysis in fossil hominins: Fourier descriptors in norma lateralis. Jun Cranial vault shape in fossil hominids: Fourier descriptors in norma lateralis. Oct Two major views of human evolution have elicited considerable controversy. These are: [1] nwd "out of Africa" hypothesis and [2] the "multiregional" hypothesis. This paper is an attempt to try to reconcile these two scenarios using hominid cranial vault data. Elliptical Fourier functions EFFs were used to describe, in visual and numerical terms, the shape of the human cranial vault in sex lateralis.

Using jpeg images, contours of the cranial vault of a large sample of hominid specimens were pre-processed in Photoshop CS and rotated in 2D space positional-orientation so that a line drawn from nasion to porion was horizontal.

The cranial vault image was then digitized with 72 closely-spaced points and submitted to a specially written routine that computed EFFs normalized by scaling size-standardization. This ensured that the representation was invariant with respect to starting point, size and orientation.

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