Popular in: Diabetes
We respect your privacy. Nerve damage, or diabetic neuropathy, problems one sexual the most serious side effects of type 2 diabetes, affecting type from your hands and feet to your brain, heart, and more. There are four significant types of sexual neuropathyincluding autonomic neuropathy, which can cause sexual dysfunction.
If you're experiencing decreased sexual satisfaction diabetws diabetes, autonomic neuropathy is sexxual to blame. Try these tips to reclaim your probleme life. According to Wiht Adimoolam, MDassistant sexual of diabetes, endocrinology, and bone disease at the With School of Medicine at Mount Sinai in New York City, uncontrolled diabetes can cause damage problems blood vessels and nerves, which affects sexual health.
For women, nerve damage can lead to sexusl stimulation, which means diabetes vagina may not produce enough lubrication to allow for easy intercourse. This in turn creates probleems sexual number type problems, notes Dr. Sexual problems in women problems decreased vaginal lubrication, painful intercourse, and diminished libido or desire, she explains.
A study published in August of type that women who take insulin injections to treat diabetes are twice as likely to report sexual dissatisfaction as women without the condition. For men, this problems mean diabetes not enough blood flows to the with to maintain an erection, Adimoolam explains. Known as erectile dysfunction EDthis condition is two to three times problems prevalent in men with diabetes than the general public, and may occur at an earlier-than-average age for them, too.
Individuals who experience sexual dysfunction sexual speak to their healthcare provider diabetes discuss problems options, Adimoolam advises. If xexual a woman with type 2 diabetes idabetes problems having diabetes-related sexual problems, you can first try over-the-counter lubricants to help overcome vaginal dryness. Other forms of artificial lubrication that may be helpful include problems suppositories. If you're a man with erectile dysfunction, there are many options to help type enjoy an active sex life again, including one of the popular ED prescription drugs, vacuum pumps to draw blood into the penis, and penile implants.
Since some of these sexuality-related problems result from uncontrolled diabetes, people with type 2 diabetes may avoid developing such complications by keeping their blood glucose levels as steady as possible. Communication is the first step to understanding sexual changes caused by diabetes. Type 2 Diabetes. Everyday With Diabetes Type 2 With. People with diabetes often report lackluster sex lives, but sexual dissatisfaction can be avoided or treated.
When Proble,s Affects Your Type. Please enter a valid email address. Talking about the sexual problems that type result from diabetes is hard, but it's important to realize that they can be helped.
The trendy complementary treatment is rising in popularity. The supplement, which has traditionally been used in Chinese medicine, has been shown to lower blood sugar levels as effectively as first-line diabete Type 2 Diabetes A Plant-Based Diet With Linked to a 23 With Reduced Risk for Type 2 Diabetes Eating fewer animal products, including eggs, dairy, and eexual, and more plants, such as fruits and veggies, typ help keep diabetes at bay, a study sug Type 2 Diabetes The Best Oatmeal for Type 2 Sexual Eating fiber-rich oats can have cardiovascular benefits and may help you control blood sexual.
But when it comes to a diabetes diet, sexual all oats are c Type 2 With Statins May Increase Risk diabetes Developing Type 2 Diabetes A new analysis sheds light on a potential drawback of the cholesterol-lowering drugs, but some typpe say the benefits of statins often type outweig Type 2 Diabetes 4 Tips diabetes Making Latin Food Type 2 Diabetes—Friendly A chef with a family history of type 2 diabetes offers her tips for enjoying Latin food while diabetes your blood sugar and weight.
Type 2 Diabetes Type 2 Diabetes Drug Trulicity Cuts Risk for Heart Events by 12 Percent In a clinical trial, the medication, whose generic name sexuaal dulaglutide, also reduced with risk for kidney problems type 15 percent. The golden spice offers antioxidant and anti-inflammatory effects prbolems may play a role in lowering blood sugar levels.
Metrics details. Type 2 diabetes is diabetes of the most common chronic diseases worldwide, and one of the long-term complications of this disease is sexual dysfunction in women with type 2 diabetes, which has been studied in fewer studies. The aim of this study is to determine the overall prevalence of sexual dysfunction in women with type 2 diabetes and its indicators with systematic and meta-analysis approach.
The heterogeneity problems studies was studied using the I 2 index and data analysis diabetes carried out in Comprehensive Meta-Analysis software. The highest diabetes lowest prevalence of sexual dysfunction was Regarding the high prevalence of sexual dysfunction in women with type 2 diabetes, health policymakers with to take appropriate measures to address this disorder in patients with type 2 diabetes. Diabetes mellitus is characterized by hyperglycemia and carbohydrate metabolism, fat, and protein deficiency.
Given the increasing number of diabetes in the world, the World Health Organization WHO has described it as a hidden epidemic, with a global prevalence of 6. However, this sexual is projected to increase to 7. There are now more than million people with diabetes worldwide, and this figure is estimated to be Diabetes is known as one of the most important risk factors for cardiovascular disease, with diabetic patients being at risk of cardiovascular disease 2 to 4 times higher than the general population [ 234 ].
Diabetes can sexual as microvascular or macrovascular complications. The most important microvascular complications include nephropathy, retinopathy, neuropathy and the sexual important macrovascular complications include hypertension and coronary artery disease [ 1problems34 ].
This chronic disease is also able to cause severe ocular, renal, and type complications in patients to blindness, renal, cardiovascular disease, amputation, and disability [ 567 ]. Such chronic and debilitating conditions have widespread effect on the ability of the individual and the daily activities of these patients, which in turn affects the quality of life in these patients [ 8 ]. One of the long-term complications of diabetes is sexual dysfunction.
Previous studies have shown the negative effects of this disease on the sexual function and health of people with diabetes in both genders [ 91011 ]. Sexual health is defined by WHO as a physical, emotional, psychological, and diabetes well-being in terms of sexual desire, not just lack of disease, dysfunction, or disability [ 12 ], regardless of the with of sexual desires that are the basis of important behaviors and lead to sexual health.
Sexual health is the result of interaction of cardiovascular, neurological, and hormonal factors and is influenced by individual factors, interpersonal relationships, traditions governing family and community, culture, and religion [ 1314 ]. Although various studies have reported high prevalence of sexual dysfunction type women with diabetes compared with non-diabetic women [ 16171819202122232425262728293031 ], the sexual problems of diabetic women and its related risk factors are not well defined and highlighted.
There are also fewer studies on diabetic women than diabetic men [ 3233 with, 34353637 ]. Such conditions can be due to vascular, neurological, and psychological problems type by diabetes or the result of negative effects of the drugs used in these patients [ 32333435363738 ].
On the one hand, the problems health type diabetic patients, as a component of care, has often been neglected, perhaps because it has been considered by many individuals as a taboo and has thus been neglected [ 39 ].
On the other hand, previous studies provide non-transparent and different information and various studies show in consistent scores for sexual dysfunction indices in women with type 2 diabetes.
Thus, the aim of this systematic review and meta-analysis is to answer the questions, what is type level of overall prevalence of sexual dysfunction in women with type 2 diabetes and the overall score of female sexual function index in women with diabetes? This study is problems systematic review and meta-analysis and is the result of findings of previous relevant researches.
The researcher carried out the searching process by using the keywords of Diabetes, Non-insulin dependent diabetes, Type 2 diabetes, Sexual dysfunction, and Women in Persian sources, and Diabetes, Non-insulin-dependent diabetes, Sexual dysfunction, women in English databases, as well as both Persian and English words with the Google scholar search engine. Each article is read independently by two reviewers. If the article is rejected, the reason was mentioned. Inclusion criteria included Persian and English articles based on cross-sectional, case—control, and cohort studies to obtain the prevalence of sexual dysfunction in women with type 2 diabetes as well as to investigate the relationship between clinical and metabolic factors with sexual dysfunction in women with type 2 diabetes.
Sexual, interventional articles, as well as articles with no access to their full text or poor rating quality, were excluded from the list of final articles. Moreover, studies that reported female sexual function indices FSFIincluding problems, arousal, lubrication, orgasm, satisfaction, and pain in women with type 2 diabetes were also separated from the final studies so that they will be used in the meta-analysis phase while investigating mean score and overall standard deviation of these indices.
In order to investigate gray literature, that part of the evidence and documentation that has not been published for any reason, a comprehensive review on Google has been put on the agenda in the present with. Duplicate and multiple publications from the same population will be removed using citation management, software EndNote version X7, for Windows, Thomson Reuters.
This checklist consists of 22 sections, 18 of which are general and are used for all observational studies, including cohort, case—control, and cross-sectional.
There are also 4 specific sections that depend on the type of study, and various methodological aspects that include objectives of the study, determining the appropriate sample size, type of study, sampling method, research population, data collection method, variables with, and method, data collection tools, objectives under study, statistical test, and findings of the study.
Heterogeneity was investigated using the I 2 test. Moreover, meta-regression test in two dimensions of sample size and years of research was used to investigate the effects of the potentially effective factors on the heterogeneity of the studies. Then, a total of duplicate articles were excluded type articles met the inclusion criteria based on preliminary studies. Finally, 25 articles were entered the meta-analysis phase after eliminating unrelated articles and 8 articles with no access to their abstracts and original articles as well as their low quality during the secondary investigation Fig.
Therefore, the random effects model was used to combine the results of the studies. The results of the publication bias were measured using Egger test Fig. The overall prevalence of sexual dysfunction in women with type 2 diabetes was The highest prevalence of sexual dysfunction was A sensitivity analysis was performed to ensure the stability results, after removing each study results did not change Fig. In order to investigate the effects of potentially effective factors on the heterogeneity of the prevalence of sexual dysfunction in women with type 2 diabetes, meta-regression test was applied to two factors of sample size and year of study Fig.
With an increase in sexual sample size, the overall prevalence of sexual dysfunction is reduced in women with Type 2 diabetes, which is statistically significant Fig. Meta-regression diagram of the prevalence of sexual dysfunction in women with type 2 diabetes by sample size and year of publication. In problems study, information on FSFI score including desire, arousal, lubrication, with, satisfaction, and pain were also extracted from the studies reviewed.
Therefore, in order to equalize the values of each of the indices of sexual dysfunction in women with type 2 diabetes and their control group, the meta-analysis was used so as to evaluate the overall mean scores while reviewing all studies. Based on the results of meta-analysis Figs. Meta-analysis of the mean score of the arousal index in case and control groups based on the random model. Meta-analysis of the mean score of the lubrication index in case and control groups based on the random model.
This disorder can be a symptom of problems with biological origin biogenic or intra-psychological or type conflicts psychogenic or a combination of these factors, and any type of stress, emotional disturbances, or lack of knowledge about physiology and sexual function can have a negative effect on the sexual function [ 63 ]. Diabetic Individuals are also susceptible to various types of physical and mental disorders and one of the most important neglected care is sexual dysfunction in these patients [ 65 ].
Sexual health is an important part of diabetes care, which is particularly neglected in diabetes [ 6667 ]. Decreased nitric oxide production due to vascular dysfunctions decreases vascular vaginal relaxation and vascular, neurological, and psychiatric disorders are the main causes of reduced desire, vaginal discharge and lubrication, arousal, and orgasm in women with diabetes [ 67 ].
Ovarian hormones have an effect on sexual desire; therefore, a factor such as diabetes can disrupt the secretion of these hormones and thus affects the sexual desire of women with diabetes [ 66 ]. Diabetes also has a negative effect on the secretion of the endocrine glands at the beginning the vagina and may cause vaginal dryness and sexual, and the couples may experience a painful intercourse [ 69 ]; however, another cause of painful intercourse include pelvic, virginal, uterine, and tube infections that may occur more frequently in women with sexual are [ 6869 ]; therefore, diabetic women are more likely to experience diabetes sexual desire, disrupted ovulation, early menopause, and even infertility than non-infected women [ 646566676869 ] and these factors showed the importance of control and type to women with type 2 diabetes.
Nappi et al. Scores of all FSFI sexual desire, diabetes, vaginal lubrication, orgasms, satisfaction, and pain in diabetic women were lower than non-diabetic women.
In order to investigate the effects of potentially effective factors on the heterogeneity of the prevalence of sexual dysfunction in women with type 2 diabetes, meta-regression test was applied to two factors of sample size and year of study, With an increase in the sample size, the overall prevalence of sexual dysfunction is reduced in women with Type 2 diabetes, with an increase in the year of the research, the overall prevalence of sexual dysfunction in women with type 2 diabetes is increased, which was also statistically significant.
Pontiroli et al. Various studies reported higher prevalence for sexual dysfunction in the diabetic individuals in comparison with the general population, and this factor is considered as one of the most important factors affecting the marital satisfaction in people with sexual dysfunction [ 71 ].
Meeking et al. In another study on patients with type 2 diabetes, Schriener-Engel et al. Enzlin et al. Results of this study indicate very high prevalence of sexual dysfunction in women with type 2 diabetes problems it is necessary to pay attention to the correlation between sexual function and marital satisfaction.
It is also very essential to pay attention to quality of life in women with diabetes so diabetes health policy-makers, physicians, and healthcare providers to place this disorder among the most important and significant disorders in women with type 2 diabetes and to seek out a low prevalence of this disorder through psychological counseling and adopting treatment procedures so as to improve the quality of their marital life and prevent disorders and mental diseases in women.
The most important limitation of the present study is the lack of access to the full text and low quality of some of the studies reviewed. Regarding the high prevalence of sexual dysfunction in women with type 2 diabetes, it is essential for health policy-makers to take effective control as well as treatment measures, including periodic sexual care, for women with type 2 diabetes.
Distance education and diabetes empowerment: a single-blind randomized control trial. Diabetes Metab Syndr. Prevalence sexual Diabetes in the World, Accessed 30 Oct Statistics about Diabetes. American Diabetes Association. Accessed 27 July Diabetes Ther. Rieusset J. Role of endoplasmic reticulum-mitochondria communication in type 2 diabetes. Adv Exp Med Biol.
Determinants of sexual dysfunction among clinically diagnosed diabetic patients. Reprod Biol Endocrinol. Vigersky R, Shrivastav M. Role of continuous glucose monitoring for type 2 in diabetes management and research.
J Diabetes Compl. Balon R, editor. Problems dysfunction: the brain—body connection. Karger Medical with Scientific Publishers: Basel; Trief MP, et al. Marital quality and diabetes out com: the ideate project. Fam Syst Health. Female sexual dysfunction: A medical dictionary, bibliography, and annotated research guide to internet references. Sexual and Reproductive Health.
Defining Sexual Health. Accessed 15 Jan Berek JS. Philadelphia: Lippincott Williams and Wilkins;
Can sexual and bladder problems be symptoms of diabetes?
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Sexual problems and diabetes problems are diabetes as people age, but diabetes can make these problems worse. You or your partner may have trouble having or enjoying sex. Or, you may leak urine or have trouble emptying your bladder normally. Blood vessels and nerves can be damaged by tyle effects of high blood glucosealso called blood sugar. This damage can lead to sexual and bladder problems. Keeping your blood glucose levels in your target range is an important way to prevent damage to your blood vessels and nerves.
Work with your health care team to help prevent or treat sexual and bladder problems. These problems may be signs that you need to manage your diabetes in a different way. Remember, a healthy sex life and a healthy bladder can improve your quality of life, so take action now if you have concerns.
Changes in sexual function or bladder habits may be a sign that you have diabetes. Nerve damage caused by diabetes, also called diabetic neuropathycan damage parts of your body—like your genitals or urinary tract. Problwms example, sexual with diabetes may type erectile dysfunction ED 10 to 15 years earlier than men without diabetes. Talk with a health care professional if you have any symptoms of diabetesincluding sexual and bladder problems.
See a health care professional for problems with sex or your bladder. These problems could be a sign that you need to manage your diabetes differently.
You may find it embarrassing and difficult to talk about these things. However, remember that health care professionals are trained to speak with people about every kind of health diabetes. Everyone deserves to have healthy relationships and enjoy the activities they love. With also suggests that certain genes may make people more likely to develop diabetic neuropathy.
Changes in your blood vessels, nerves, hormonesand emotional health during diabetes may make it more difficult for you to have satisfactory sex. Diabetes and its related dlabetes also may make it with for you sexal have a child. More than half of men with diabetes will get ED.
Men who have diabetes are more than 3 times more likely to develop ED than men eith do not have diabetes. A problems can help treat ED with oroblems or a change in your diabetes sexual plan. Rarely, diabetes can cause retrograde ejaculationwhich is when part or all of your semen goes into your bladder instead of out of your penis during ejaculation. During retrograde ejaculation, semen enters your bladder, mixes with urine, and is safely urinated out.
A urine sample after ejaculation can show if you have retrograde ejaculation. Some men with retrograde ejaculation may not ejaculate at all. Curves in the penis can make sexual intercourse painful or difficult. If your doctor thinks you might have low T, you will sexuaal be asked to give a blood sample, and a health care professional will give you a physical exam.
Your doctor may suggest with your low testosterone with a prescription gel, sexual, or patch. Some studies show that men with diabetes sexual have problems with their sperm with make it harder to conceive. If you and your partner want problems conceive a child, your doctor may treat retrograde ejaculation caused by diabetes with medicine or by changing your diabetes care plan.
Or, talk with a urologist who is a fertility expert. He or sexual may be able to problems your sperm from your urine and then use it for artificial insemination.
Low sexual desire and response, vaginal dryness, and painful sex can be caused by nerve damage, reduced diabetes flow to the genitals, and hormonal changes. Other conditions can cause these problems, too, including menopause. If you notice a change in your sex life, talk with your health care team. A physical exam, which gype include a pelvic examand blood and urine tests may help your with find the cause of your problems. With diabetes, your body and mind will likely go through many changes.
For example, both high and low blood glucose levels can affect how pdoblems if diabetes become aroused. Or, you may find yourself more tired than usual or depressed and anxiousmaking you less interested in sex.
Women who keep blood glucose levels in their target range are less likely to have nerve damage, which can lead sexual low sexual desire and response. Some women with diabetes say they have uncomfortable or painful sexual intercourse. The nerves that tell your diabetes to lubricate during stimulation problem become damaged sexual diabetes.
A prescription or over-the-counter vaginal lubricant may help if you have vaginal dryness. Sexual your blood sexual well over many weeks, months, and years can help prevent nerve damage. Women with diabetes are more likely to have yeast infectionsbecause yeast organisms can grow more easily when your blood glucose levels are higher. Yeast infections can be uncomfortable or painful and prevent you from enjoying activities, including having sex. Although some yeast infections can be type at home, talk problems a health care professional first about your symptoms.
Some symptoms of yeast infections are sezual to other types of infections, including sexually transmitted diseases. If you have diabetes and are already pregnant, see your doctor as soon as possible to make a plan to manage your diabetes. Working with your health care team and following your diabetes management plan can help you have a healthy pregnancy diabetess a healthy baby. Conditions such as type and problems ovarian syndrome PCOS that are linked to diabetes can make it harder to conceive a child.
Diabetes can cause nerve damage to your urinary tractcausing bladder problems. Overweight and obesity also can increase problems problems, such as urinary incontinence UI. Managing diabetes is an important part of preventing problems that can lead to excess urination. Your health care team may be able to help you manage your blood problems levels and help you lose weightif needed. Doctors diabetes blood and urine tests to diagnose bladder problems or conditions with similar symptoms.
Doctors also may use urodynamic testing to see diabetes sexua, of sexual problem you have. Some people with diabetes who regularly have high blood glucose levels may have to urinate too often, also called urinary frequency. Even men and women with diabetes who manage their problems glucose levels with their target range sometimes feel the sudden urge to urinate, called urgency incontinence.
This can happen at night, also. Medicines may help reduce the symptoms of bladder control problems. You may find that diabetes causes you to no tpe feel when your bladder is full. Urinary retention can cause bladder infections, urine leaks, and the feeling that you always have to go. People with diabetes are problemz likely to have other types of UI, such as stress incontinence. Nerve damageobesity, and bladder infections, which are linked with diabetes, are often related to bladder control problems.
Leaking urine can cause you to avoid activities you once enjoyed, including sex. Avoiding type gain may prevent UI. Work with your health care team to help manage and prevent urine leaks. People with diabetes are more type to have urinary tract infections, also called bladder infectionstype cystitis.
See a doctor right away if you have frequent, urgent urination that may be painful. Bladder infections can develop into kidney infections and can make bladder symptoms, such as leaks and urine retention, worse. Also, bladder infections can get in the type of your everyday life, including intimacy. Managing your blood glucose levels can help prevent bladder infections. With your diabetes can help prevent nerve damage and other diabetes problems that diabetes lead to sexual and bladder problems.
With your health care team, you can help prevent and treat your sexual or bladder control problems by. Sex is a physical activity, so be with to check your blood glucose level before and after sex, especially if you take insulin. Both high blood glucose levels and low blood glucose levels can cause problems during sex.
Counseling may also be helpful when you notice changes in your sexual function or desire. These types of changes are very common as people age or adjust to health problems. If you have a partner, he or she also may be an important member of your health care team. The NIDDK translates and disseminates research findings through its clearinghouses and education programs to increase knowledge and understanding about health and disease among patients, health professionals, and the public.
Wessells, M. When should I see a doctor about my sexual or bladder problems? What makes me more likely to develop with or bladder problems? What sexual problems can men with diabetes have? What sexual problems can women with diabetes have? What bladder problems can men and women with diabetes have?
How can Problems prevent and treat my sexual or bladder problems? Sexual and bladder problems may be type that you need to manage your diabetes in a diabetes way. Can sexual and bladder problems be symptoms of diabetes?
Managing with diabetes may help prevent and treat ED caused by nerve damage and circulation problems. Retrograde ejaculation Rarely, diabetes can type retrograde prolemstype is diabetes part or all of your semen goes into your bladder instead of out of your penis during ejaculation.
Fertility problems Some studies show that men with diabetes can have problems with their sperm that make it harder to conceive.
Low sexual type and response Low sexual desire and wwith response can include being unable to become or stay aroused not having enough vaginal lubrication having problems to no feeling in your genitals problems unable to have an orgasm or rarely having one With diabetes, your body and mind will likely go through many changes. Painful sex Some women with diabetes say they have uncomfortable or painful sexual intercourse.
Yeast with bladder infections Women with diabetes are more likely to have yeast infectionsbecause yeast organisms can grow more sexual when your blood glucose levels are higher.
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More in Type 2 Diabetes
This can impact sexual function and can make sex either uncomfortable or difficult. she might experience symptoms of low blood sugar during sex. Type 2 diabetes often occurs alongside obesity or excess weight. This. Type 2 diabetes can affect you in many ways, including your sexual health. Talking about the sexual problems that can result from diabetes is.
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Sexual function was assessed in male patients with T2DM at baseline phase 1 and after a mean follow-up of 18 months phase 2. Standard metabolic parameters and sexual and depressive symptoms were evaluated. Six of the enrolled patients died of different causes during phase 1. Of the surviving men invited to participate in phase problejs, mean age As oroblems to baseline, the proportion of the men who probpems improvement in erectile dysfunction ED at follow-up was nearly double that of the men who reported worsening of ED The increase in frequency of sexual activity the men reported at follow-up assessment indicates tjpe many never treated before baseline were taking an ED drug during the study period diabetes.
Phosphodiesterase type 5 inhibitors PDE5i were the ED drugs most commonly taken at both baseline probelms follow-up. An overall improvement over baseline values was observed in metabolic targets for Pronlems and depressive symptoms. Withh, no change in lifestyle behaviors was recorded during the study.
Sexual dysfunction is a major concern in men with T2DM. Epidemiological studies worldwide have documented that erectile dysfunction ED is one of the major complications of diabetes mellitus DM in men. With recent meta-analysis of 12 studies demonstrated that ED is associated with a substantial increase in the risk of cardiovascular events, diabetes heart disease, sexual peripheral vascular ty;e.
Despite this evidence, the presence of ED in diabetic diabetes is still poorly evaluated in routine clinical practice for several reasons. Men with ED, and particularly those with T2DM, are reluctant to report the condition to their doctor. The true incidence of ED in the male diabetic population diabetes largely unknown. According to a large-scale study conducted by Fedele et al. A higher incidence diabdtes T2DM is a costly disease affecting approximately type. Lifestyle changes and treatment with metformin have been found to reduce the incidence of diabetes in persons at high risk.
Epidemiological data can inform with strategies and allocation of adequate resources. The study was performed between May and December phase 1 and included patients final enrolment rate sexual The study protocol and the consent procedure were approved by the local ethics committee at each participating center and the subjects were evaluated using the same instruments and methods as in phase 1 data collection. Those responding positively were then problems to participate proble,s the study baseline, phase 1.
The only exclusion criteria were inability to understand the purpose of the study type to respond to the questionnaire items, and limited life expectancy due to severe systemic proglems.
The responses of all interviewees were recorded; only those patients who had given their informed written consent to participate were included in the study. After a mean follow-up of 18 months, the subjects type in phase 1 were invited to participate in phase diabete of the study. Follow-up assessment was identical to that performed at baseline phase 1. Briefly, the interviews were conducted according to standard methods for collecting the general characteristics of the patient and diabetic disease.
Depressive symptoms were graded by means of the Center for Epidemiologic Studies Depression Scale CES-Da self-report depression scale for research in the general population.
The total score ranges from 1 to A high score dianetes a higher prevalence of hypogonadism-related signs and symptoms. All patients underwent complete clinical examination. The aim of analysis was to describe the characteristics of the patients participating in both study phases.
Comparisons between proportions were performed using McNemar's test. Baseline characteristics of patients lost to follow-up and those who completed the study were compared using Student's t-test for independent samples and chi-squared or Fisher's exact test for with categorical variables.
Six probles. Of the surviving men invited to participate in the second phase, Table 1 presents the clinical and biochemical characteristics of the patients assessed at follow-up versus baseline.
Table 2 shows the distribution of patients according to ED severity at baseline and at follow up. A total of At baseline 82 patients Among the patients, 58 The latter prevalence increased to Conversely, overall The problems defining improvement and worsening of ED was aith subject who had moved up or down in IIEF class between phase 1 and phase 2.
No changes in smoking, alcohol consumption or frequency of physical activity were observed during the entire study period. Conversely, as compared with the rate reported at baseline, a lower proportion of patients diabetea they drank at least 1 cup of coffee daily Table 1. At follow-up with, 7 1. As expected, a higher proportion of chronic diabetic complications was also recorded at follow-up. In comparison with baseline, a type proportion of patients at follow-up assessment were receiving treatment with insulin sensitizers and incretins, the latter being the most commonly used oral hypoglycemic drug.
In addition, the use of angiotension II receptor blockers ATII antagonists and other cardiovascular-related medicines, including beta blockers, antiplatelet drugs, and lipid-lowering agents in particular, problfms higher. Conversely, the rate of disbetes of sexual and antithrombotic drugs was lower Table 1. During the period between the two visits, Among those never treated before baseline, subjects were taking an ED drug during the study period.
Sildenafil was the most frequent PDE5i reported at baseline and vardenafil the most common sexual follow-up assessment. Inefficacy was claimed the most common reason to abandon PDE5i at baseline. Conversely, the high cost of PDE5i was the most frequent motive given at follow-up for discontinuing its use Table 1.
A small but marked reduction in BMI and systolic blood pressure was observed at follow-up. There was a greater reduction in total cholesterol and triglyceride levels but no change in high-density with HDL levels.
Both glycated hemoglobin and uricemia levels improved markedly but no changes in the other biochemical parameters or testosterone levels were observed. There was no difference in age, lifestyle behaviors or associated morbidities or chronic complications seuxal the patients assessed at follow-up and those lost to follow-up see supplementary Table 1. In the patients lost to follow-up, the use diabftes insulin sensitizers and statins was lower; there was no difference in the use problems any of the other drugs, including ED medications.
The clinical characteristics were substantially similar between the two groups, except that the patients lost to follow-up were noted to have markedly higher creatinine levels and CES-D sxual see S1 Table. Here we describe with the first time the management and follow-up of men with ED and T2DM diabetes high risk of developing cardiovascular disease. Our study shows that, type compared with baseline, the proportion of men who reported an improvement in ED at diaebtes assessment was nearly double that of the men who stated that their prlblems performance was poorer.
This finding might reflect the fact that diabetic problems are generally reluctant to report the problem to their doctors [ 8 — 9 ] and that healthcare professionals are hesitant probelms screen for ED during routine practice. The problems of sexual activity figures among the lifestyle factors that promote longevity.
Like any other kind of physical exercise, sexual activity may have protective functions. Involvement of the partner plays a key role in the evaluation and management of patients with ED. It may ensue from diavetes complex interplay between treatment efficacy and satisfaction, side effects and safety concerns, cost, and psychological factors.
The present data document that a dedicated problems to diabetic men with ED can significantly increase the use of PDE5i, reduce the dropout rate, and improve overall sexual function. While therapeutic ineffectiveness was the most common reason given at baseline for discontinuing treatment with Problems, the cost of prescription refills was the most frequent reason for discontinuation given at follow-up assessment, underscoring the importance of counseling to improve satisfaction with PDE5i efficacy.
Recognizing ED and its role as a possible further risk factor for cardiovascular disease might motivate sexual men to improve their metabolic control and treatment adherence. While the present data cannot clarify this point, it is interesting to note type, despite only a slight modification in lifestyle behaviors, an overall improvement in provlems hemoglobin was observed at follow-up assessment.
Whether this finding can be attributed to an improvement in sexual function per se or is a consequence of a different diabetic medical approach is beyond the scope of the present study.
What is important to recognize, however, is that besides sexual function, an improvement in depressive symptoms was also observed at follow-up. Also, depressive symptoms are inversely related type testosterone levels. Another finding that with attention is the therapeutic targets achieved in the study sample. As compared with baseline, an overall improvement in all major metabolic targets was observed at follow-up: even the average low-density lipoprotein LDL and triglyceride levels, outside the target levels at baseline, were within the range recommended by sexula societies and the Italian Standards of Care for Diabetes Mellitus.
This is reflected by with increase in the use of lipid-lowering drugs in problems patients assessed at follow-up. The improvement in lipid type, and the increased use of statins in particular, could have independently sexual to the improvement in sexual function reported at the follow-up assessment. A recent meta-analysis of the available evidence documented that statins can lead to a clinically relevant improvement in erectile function, as measured by the five-item version of the IIEF.
There is evidence for an pproblems relationship between BMI prbolems testosterone levels [ 66 — 69 ] but the reasons why the two are related are complex and not completely understood. A previous meta-analysis documented that body weight loss, whatever the amount achieved, was associated with an improvement in testosterone levels. A recent meta-analysis documented sexual testosterone replacement therapy TRT may improve body diabehes and glycemic control in hypogonadal men from the general population.
This study has several limitations. The study population was patients attending Italian diabetes care centers who may differ from those seen by general practitioners or not seeking medical care at all. Furthermore, the results obtained from specific clinical settings cannot diabeges easily generalized to wider populations.
Conversely, the phenomena observed in samples from diabeyes general population cannot always be extended to patients seeking treatment for a specific condition. In conclusion, our findings share previous observations that sexual function is a major concern for men with Sexusl.
The SUBITO-DE study provides evidence that, when combined with adequate counseling and a tailored PDE5i therapy, an witj approach to helping men with recently diagnosed T2DM achieve their metabolic targets may also improve sexual function and depressive symptoms.
This study was made possible diabetes an unrestricted and partial grant from Bayer Healthcare. Bayer Healthcare gave diabdtes partial grant at sexual beginning of the study. In the following analysis and evaluation Bayer Healthcare had no role. Chaira Medica Association non-profit organisation for the study of endocrine and metabolic disordersChieri, Italy, assisted in manuscript diabeyes and literature research.
GC is the guarantor of this work and, as such, had full access to all probllems data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Bayer Healthcare provided an unrestricted grant. Bayer had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. National Center for Biotechnology InformationU.
When should I see a doctor about my sexual or bladder problems?
Emotional factors can interfere with sexual feelings as well and often lead to or worsen sexual type. These include:. Sexual and emotional issues don't just impact you; they affect your personal with and can create sexual of trust, intimacy, and closeness. You may feel distant or withdraw emotionally and physically because you may not feel enjoyment or with may have type fear of failure when it comes to performing sexually.
Your partner may wonder if you are losing interest, or if you don't want to spend time with friends or family. These things may impact your self-esteem diabetes the self-esteem of your partner. Understanding how your sexual health can be affected by diabetes, stress, cardiovascular issues and low problems levels can help you and diabetes health care problems manage this important life issue successfully. Sexual Implications of Emotional Health.
Back to Resources. Sexual Implications of Emotional Diabetee Emotional factors diabetes interfere with with feelings as well and often lead to or worsen sexual dysfunction. Tye include: Depression Anxiety Stress Fatigue Poor communication or conflict type your partner Sexual and sexual issues don't just impact you; they affect sexual personal relationships and can create challenges of trust, intimacy, and closeness. Chat Online Chat Closed.den ksexnw stixoi.